Found 210 matching trials
Ruxolitinib Phosphate and Chemotherapy Given Before and After Reduced Intensity Donor Stem Cell Transplant in Treating Patients With Myelofibrosis PHASE1 This pilot clinical trial studies the side effects and best dose of ruxolit...
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City of Hope Medical Center
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Use of Thalidomide, Lenalidomide, Carfilzomib, Bortezomib and Vorinostat in the Initial Treatment of Newly Diagnosed Multiple Myeloma Patients PHASE3 The purpose of this study is to compare a standard chemotherapy regimen of ...
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112 sites UK wide
Treatments Being Tested
Induction (intensive pathway) - cyclophosphamide, lenalidomide, & dexamethasone (CRD) regimen Induction (intensive pathway) - cyclophosphamide, thalidomide, & dexamethasone (CTD) regimen Induction (intensive pathway) - carfilzomib, cyclophosphamide, lenalidomide, & dexamethasone (CCRD) regimen Induction (non-intensive pathway) - cyclophosphamide, lenalidomide, & dexamethasone attenuated (CRDa) regimen Induction (non-intensive pathway) - cyclophosphamide, thalidomide, & dexamethasone attenuated (CTDa) regimen Consolidation (intensive & non-intensive pathways) - bortezomib, cyclophosphamide, & dexamethasone (VCD) regimen Maintenance (intensive & non-intensive pathways) - lenalidomide maintenance Maintenance (intensive & non-intensive pathways - protocol v5.0 only) - lenalidomide plus vorinostat maintenance High dose melphalan therapy and autologous stem cell transplant (intensive pathway only) Learn More & Join Trial
Carboplatin, Melphalan, Etoposide Phosphate, Mannitol, and Sodium Thiosulfate in Treating Patients With Previously Treated Brain Tumors PHASE1 This phase I/II trial studies the side effects and best dose of melphalan w...
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University of Minnesota/Masonic Cancer Center
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A Pilot Study of Immunotherapy Including Haploidentical NK Cell Infusion Following CD133+ Positively-Selected Autologous Hematopoietic Stem Cells in Children With High Risk Solid Tumors or Lymphomas PHASE1 This is a pilot clinical trial investigating the addition of haploidentical...
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St. Jude Children's Research Hospital
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TCRαβ-depleted Progenitor Cell Graft With Early Memory T-cell DLI, Plus Selected Use of Blinatumomab, in naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies PHASE1 This is a phase I, prospective clinical trial studying the safety and feasi...
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St. Jude Children's Research Hospital
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Bortezomib, Thalidomide, and Dexamethasone After Melphalan and Stem Cell Transplant in Treating Patients With Stage I-III Multiple Myeloma PHASE2 RATIONALE: Bortezomib and thalidomide may stop the growth of multiple myelo...
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City of Hope Medical Center
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High Dose Chemotherapy and Autologous Transplant for Neuroblastoma NA This is a standard of care document, outlining the therapy for children wit...
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Masonic Cancer Center, University of Minnesota
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Microdose Study of Melphalan, Bortezomib and Dexamethasone EARLY_PHASE1 The purpose of the study is to identify specific genes that are up- or down...
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Department of Haematology, Aalborg University Hospital
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Two Step Haplo With Radiation Conditioning PHASE2 This phase II clinical trial evaluates whether a modified modality of condi...
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Sidney Kimmel Cancer Center at Thomas Jefferson University
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The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation PHASE1 Background:
Blood cancers (such as leukemias or lymphomas) often do not re...
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